The “17 + 1” Mechanism

I-17: The Mechanism of Gonadal Sex Determination

Background In mammals, a single exon gene SRY on the Y-chromosome is activated in the XY gonadal primordium and initiates a cascade of molecular and morphological events leading to testicular differentiation. SRY-encoded protein (SRY) is a transcription factor harboring a HMG-box DNAbinding motif that upregulates SOX9, which encodes another transcription factor sharing the DNA binding motif wit...

autopsy: the changing trends .......... ijmtfm (2011) 1(1): 17-23

investigative dissection of a dead body primarily to find out cause of death is known as postmortem examination or necropsy. medicolegal autopsy or forensic autopsy is performed following instructions of legal authority in sudden, suspicious, obscure, unnatural or criminal deaths. autopsies are of two types i.e. medico legal autopsy and pathological or hospital autopsy. traditional procedures o...

cover Vol.17- No.1 February 2020

Linear Regression ( 1 / 1 / 17 )

Jcb_201404079 1..17

The Rockefeller University Press $30.00 J. Cell Biol. Vol. 207 No. 4 517–533 www.jcb.org/cgi/doi/10.1083/jcb.201404079 JCB 517 *A. Juin and J. Di Martino contributed equally to this paper. Correspondence to Violaine Moreau: [email protected]; or Frédéric Saltel: [email protected] Abbreviations used in this paper: CMV, cytomegalovirus; DDR, Discoidin domain receptor; GAPDH, glyce...